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Characterization of recombinant #Trypanosoma brucei gambiense# translationally controlled tumor protein (r#Tbg#TCTP) and its interaction with #Glossina# midgut bacteria

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Bossard G., Bartoli M., Fardeau M.L., Holzmuller P., Ollivier B., Geiger A.
2017

In humans, sleeping sickness (i.e. Human African Trypanosomiasis) is caused by the protozoan parasites Trypanosoma brucei gambiense (Tbg) in West and Central Africa, and T. b. rhodesiense in East Africa. We previously showed in vitro that Tbg is able to excrete/secrete a large number of proteins, including Translationally Controlled Tumor Protein (TCTP). Moreover, the tctp gene was described ...

Maladies des animaux; Autres thèmes

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