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Resveratrol-Linoleate protects from exacerbated endothelial permeability via a drastic inhibition of the MMP-9 activity

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Shamseddin A., Crauste C., Durand E., Villeneuve P., Dubois G., Pavlickova T., Durand T., Vercauteren J., Veas F.
2018

Gelatinolytic matrix metalloproteinases (MMP-2, -9) play a critical role not only in mammals physiology but also during inflammation and healing processes. The natural stilbenoid, resveratrol (RES), exhibits potent antioxidant effects, in a hormetic mode of action, and is known to inhibit MMP-9. However, RES administration exhibits major issues, including poor bioavailability and water ...

Physiologie et biochimie animales; Maladies des animaux

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