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Bioactivity-guided mass spectral net working reveals a new set of allbicidin derivatives from #Xanthomonas albilineans#

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Dang T., Petras D., Pesic A., Cociancich S., Royer M., Dorrestein P.C., Süssmuth R.
2016

Albicidin is produced by the sugarcane pathogenic bacterium Xanthomonas albilineans and is a potent antibiotic specifically targeting the bacterial DNA gyrase with an IC50 value in the nanomolar range. The structure of albicidin, which has remained unsolved for more than three decades since its first description, has been solved by a combination of extensive NMR and HR-MS/MS experiments. An ...

Maladies des plantes

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