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The global distribution and spread of the mobilized colistin resistance gene #mcr-1#

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Wang R., van Dorp L., Shaw L.P., Bradley P., Wang Q., Wang X., Jin L., Zhang Q., Liu Y., Rieux A., Dorai-Schneiders T., Weinert L.A., Iqbal Z., Didelot X., Wang H., Balloux F.
2018

Colistin represents one of the few available drugs for treating infections caused by carbapenem-resistant Enterobacteriaceae. As such, the recent plasmid-mediated spread of the colistin resistance gene mcr-1 poses a significant public health threat, requiring global monitoring and surveillance. Here, we characterize the global distribution of mcr-1 using a data set of 457 mcr-1-positive sequenced ...

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