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Comparison of the efficiency of different newcastle disease virus reverse genetics systems

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Liu H., Servan de Almeida R., Gil P., Albina E.
2017

Rescue of negative-sense single-stranded RNA viruses ((?)ssRNA virus), generally requires the handling of a large number of plasmids to provide the virus genome and essential components for gene expression and genome replication. This constraint probably renders reverse genetics of (?)ssRNA virus more complex and less efficient. Some authors have shown that the fewer the plasmids, the more ...

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