The transcriptomic analytical level determines the human monocyte-derived macrophage response toward either the infectious agent or the host

Holzmuller P., Nirdé P., Vezilier F., Chuchana P.
2016

Macrophages exhibit multifunctional activity and play a central role in the response to infectious agents. It is commonly accepted that the plasticity of the response of macrophages depends on the type of stimuli. Here we re-evaluate whether the macrophage response is only dependent on the stimulus. We analyzed the transcriptomic profile of monocyte-derived macrophages (MDMs) that were activated ...

Maladies des animaux; Autres thèmes