The #O#-carbamoyl-transferase Alb15 is responsible for the modification of albicidin

Petras D., Kerwat D., Pesic A., Hempel B., Von Eckardstein L., Semsary S., Arasté J., Marguerettaz M., Royer M., Cociancich S., Süssmuth R.
2016

Albicidin is a potent antibiotic and phytotoxin produced by Xanthomonas albilineans which targets the plant and bacterial DNA gyrase. We now report on a new albicidin derivative which is carbamoylated at the N-terminal coumaric acid by the action of the ATP-dependent O-carbamoyltransferase Alb15, present in the albicidin (alb) gene cluster. Carbamoyl-albicidin was characterized by tandem mass ...

Autres thèmes; Maladies des plantes